The Department of Molecular Biology functions with the Molecular Diagnosis of Infectious Diseases and HLA Tissue Typing for Transplant programmes. This is the only lab in the state meeting the international standards for a molecular diagnostics facility. Cross matching and tissue typing was started for the first time in the state of Kerala. The method is more accurate and provides more information on the HLA antigens. Gene testing was started with thrombophelia genetics wherein Factor V Leiden and Prothrombin genes are analyzed for their mutations.

The molecular biology laboratory undertakes specialised investigations such as PCR based analysis and HLA typing.