29th Annual Convention of IACR and Symposium
on
"Biology of Cancer Stem cells"
20-23 February 2010 Scientific Programme
Venue: Amrita Institute of Medical Sciences and Research Centre, Cochin
20/02/09 Saturday
2.00 - 5.00 PM Registration & Tea
5.00 - 6.00 PM Inauguration
6.00-7.00PM Inaugural address : Prof. E.P.Reddy
Director, Fels Institute of Cancer Research,
Philadelphia, USA-
”Targeting the protein kinome for cancer therapy”
7.00 -8.00 PM Chairperson: Dr. Rita Mulherkar,
President IACR IACR oration by Dr.Naresh, Imperial College, London
“Understanding Lymphoma – a vehicle for translational research in oncology”
8.00 PM Dinner
Venue: AIMS
21/02/10 Sunday
8.00 AM Breakfast
Venue: AIMS
9.00 - 11.00 AM Session I - Cell Signaling and Cancer
Chairpersons: Dr. Asha Ramachandani/ Dr.Prasanna Venkatraman,
ACTREC, Mumbai
9.00 - 9.30 AM Dr.Harsha Gowda,
Institute of Bioinformatics, Bangalore
“Proteomic approaches to identify activated tyrosine kinase signaling pathways in cancers"
9.30 - 10.00 AM Dr.Prasanna Venkatraman,
ACTREC, Mumbai
“Structure Guided Modeling to elucidate Novel Functions in Proteins”
10.00 - 10.30 AM Dr.Pradeep Raghavan
Weizmann Institute of Science,Israel
“HER2-associated breast cancer signature using a 3D culture model”
10.30 – 11 AM Dr.Pradeep Raghavan
Weizmann Institute of Science,Israel
“HER2-associated breast cancer signature using a 3D culture model”
10.30 – 11 AM Dr.V.K.Nandacoori
NII, Delhi
“ Role of cell signaling event in modulating the functions of nucleoporin Tpr”
11.00 - 11.30 AM Tea
11.30 - 1.00 PM Session II Molecular Genetics of Cancer I
Chairpersons : Dr. Chitra Mandal,
Indian Institute of Chemical Biology, Kolkata
11.30 - 12.00 AM Dr.G.C.Kundu
NCCS, Pune
“ Stroma and tumor-derived osteopontin: role in inflammation, angiogenesis and cancer”
12.00 - 12.30 PM Dr.C.Mandal,
II CB, Kolkata
“Sialic acids in Haematopoietic stem cells of childhood acute lymphoblastic leukemia”
12.30 - 1.00 PM Dr.A.Suri,
NII, Delhi
“Small Interfering RNA- Mediated Down – Regulation of SPAG9 Inhibits
Cervical Tumor Growth”
1.00 - 2.00 PM Lunch
9.00 - 11.00 AM Session III Clinical and Molecular aspects of GI Malignancies
Chair person: Prof. V.Balakrishnan
2.00 - 2.30 PM Prof. Balakrishnan,
AIMS, Kochi
“Chronic pancreatitis and pancreatic cancer- is there a link”
2.30 - 3.00 PM Dr.K.M.Mohandas,
Tata Memorial Hospital
"Enigmatic Epidemiology of Gastrointestinal Cancer in South Asia"
3.00 - 3.30 PM Dr.Akhilesh.Pandey,
Johns Hopkins School of Medicine, Baltimore
“A multi-pronged proteomic approach to identifying biomarkers for GI malignancies”
3.30 – 4.00 PM Dr.S.Saxena,
Safdarjung Hospital,
“ Esophageal cancer in North East India- Contribution of
genetic vis-à-vis environmental factors.”
4.00 – 5.30 PM Tea and Poster session – I
5.30 – 6.00 PM Session IV Free oral Presentations
Chairperson – Dr.Akhilesh Pandey,
Johns Hopkins School of Medicine, Baltimore
Selected Abstracts :
  • “Modulation of the function and expression of Pglycoprotein by a newly developed copper complex in NIH MDR 1 cells” – Ruma Dey Ghosh, Chittaranjan National Cancer Institute, Kolkata
  • “PSP94 as well as CRISP-3 can exert growth inhibitory effect in a cell line dependent and mutually exclusivemanner”- Bhakti Pathak, National Institute for Research in Reproductive Health, Mumbai
  • “Anticancer and antimutagenic activities of Eruca Sativa Extracts against B16F10 melanoma cell- Menka Khoobchandani”- JNCH, Bhopal
6.00 - 7.00 PM IACR Executive Committee meeting
7.00 PM Cultural Program
8.00 PM onwards Dinner
Venue: AIMS
22/02/10 Monday
8.00 AM Breakfast
Venue: AIMS
9.00 - 11 AM Session V Cancer Stem Cells
Chairperson – Prof. T.S.Ganesan, AIMS, Cochin
9.00 - 9.30 AM Dr.Sharmila Bapat,
NCCS, Pune
“Gene Expression - Protein Interaction Systems Network Modeling identifies Transformation Associated Molecules and Pathways in Ovarian Cancer”
9.30 - 10.00 AM Dr A. Rangarajan,
IISC, Bangalore
“Generation of an Immortalized Breast Stem Cell Line with a Propensity for Spantaneous Transformation”
10.00 - 10.30 AM Dr.Geetha Vemuganti,
L.V. Prasad Eye hospital, Hyderabad
“Cancer stem cells in Retinoblastoma”
10.30 – 11.00 AM Dr.Sheo Mohan Singh,
International Institute of Information Technology, Pune.
“Proteomic systems biology of (8;21) Acute Myeloid Leukemia (AML) reveals that leukemic fusion protein AML1-ETO targets a C/EBP-NM23 pathway”
11.00 - 11.15 AM Dr.Sheo Mohan Singh,
International Institute of Information Technology, Pune.
“Proteomic systems biology of (8;21) Acute Myeloid Leukemia (AML) reveals that leukemic fusion protein AML1-ETO targets a C/EBP-NM23 pathway”
11.00 - 11.15 AM Tea
11.15 – 1.15 PM Session VI Molecular Genetics of Cancer II
Chairperson: Dr.T.Rajkumar,
Adayar Cancer Centre, Chennai
11.15 - 11.45 AM Dr.Rita Mulherkar
Weizmann Institute of Science,Israel
“Preclinical Studies on Gene Therapy for Head and Neck Cancer”
11.45 - 12.15 AM Dr.T.Raj Kumar
Cancer Institute Adayar, Chennai
“Gene expression studies in cervical cancer - diagnostic, predictive
and therapeutic implications”
12.15 - 12.45 PM Dr. Krishnan Nair
Amala Cancer Centre , Trichur
“Control tumour with radiation and radio modifiers mechanistic studies in animal models”
12.45 - 1.15 PM Dr.Krishna Gupta
Indian Institute of Toxicology Research, Lucknow
“Involvement of epigenetic events in the regulation of gene expression by
inositol hexa phosphate, a Chemopreventive agent”
1.15 - 2.00 PM Lunch
2.00 – 3.00 PM Session VII Drug Development -Bench to Bedside
Chairperson: Dr.Bipin Nair
2.00 – 2.30 PM Dr.Bipin Nair,
School of Biotechnology, Amritapuri,Kollam
“Lead Development from Natural Sources”
2.30 – 3.00 PM Dr.Cartikeya Reddy,
Reddy’s Laboratories, Hyderabad
“ Biologics in Oncology”
3.00 – 3.30 PM Prof. Raghunatha Rao,
Nizam Institute, Hyderabad
“Bench to Bedside - the Role of a Cancer Clinical Trial”
3.30- 4.30 PM Tea and Poster session
4.30 – 6.30 PM Session VIII Shri Sitaram Joglekar / Smt. Mangala Bamane Award (Selected Abstracts)
Chairperson:Dr.Rita Mulherkar
Selected Abstracts :
  • “Eugenol restricts DMBA croton oil induced skin carcinogenesis in mice : downregulation of c-Myc, H-ras and activation of p53 dependent apoptotic pathway”– Debolina Pal, Chittaranjan National Cancer Institute, Kolkata
  • “Integration site of high risk HPV - a key event of cervical cancer”- Poulami Das, ACTREC, Mumbai
  • ‘Genotype-molecular phenotype correlation using lymphoblastoid cell lines from patients with multiple primary neoplasia”- Tabish Hussain, ACTREC, Mumbai
  • ‘Genotype-molecular phenotype correlation using lymphoblastoid cell lines from patients with multiple primary neoplasia”- Tabish Hussain, ACTREC, Mumbai
  • “All-Trans Retinoic Acid (ATRA) down regulates MMP-by modulating its regulatory molecules”- Anindita Dutta, Chittaranjan National Cancer Institute, Kolkata
  • Identification and functional characterization of tumor suppressor genes located within novel homozygous deletions in pancreatic cancer – Mohammed Khursheed, Laboratory of Molecular Oncology, Hyderabad
  • “Activation of Signal Transducers and activators of Transcription 3 (STAT3) in Breast Cancer: Association with Cell Proliferation and Survival”- Prabha Pillai, RCC ,Trivandrum
  • “Overexpression of histone variant H2A.1 during N - Nitrosodiethylamine induced seqential Hepatocellular arcinogenesis” – Satyajit Khare, CRI-ACTREC, Mumbai
  • “Overexpression of histone variant H2A.1 during N - Nitrosodiethylamine induced seqential Hepatocellular arcinogenesis” – Satyajit Khare, CRI-ACTREC, Mumbai
  • "Cross-regulation of Stat 3 and Wnt-a-Catenin ignaling: Implication in Cancer”-T.Mandal, Indian Institute of Chemical Biology (CSIR) Jadavpur,Kolkata
  • “Loss of function of rictor enhances MMP-9 activity and invasion, independent of PKC-α in gliomas” – G.Gowry Das. National Centre for Cell science, Pune
  • “Role of EBV encoded Latent Membrane Protein 2A (LMP2A) and small non-coding RNA (EBERs) in gastric cancer proliferation and migration” – Aditi Sengupta Banerjee, Saha Institute of Nuclear Physics, Kolkata
  • “Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase ceramide cascade mediated c-Jun N-terminal kinase pathway” – Susmita Mondal, Indian Institute of Chemical Biology, Kolkata
  • “Mutations in RUNX1 results in decrease binding affinity to its promoter binding site”- Jyoti Zack, Dr. B.R. Ambedkar Centre for Bio-medical Research, Delhi
6.30 – 7.20 PM Chairperson: Dr.Cartikeya Reddy
Key note address – Dr.Roy Bicknell,
Division of Immunity and Infection, University of Birmingham“Anti-cancer strategies targeting the tumour vasculature”
7.30 PM General Body Meeting
8.30 PM Banquet
Venue: Renaissance Hotel
23/02/09 Tuesday
8.00 AM Breakfast
Venue: AIMS
9.00 - 10 AM Chairperson: Dr.Sharmila Bapat
Key note address- Prof.A.Dharmarajan, School of Anatomy and Human Biology,
Perth, West Australia“Secreted Frizzled Related Protein 4: A novel Angiogenesis Inhibitor”
10.00 - 11.15 AM Dr.Bindu Dey
Advisor, DBT
“Cancer Research in India Capacity, Resources And Opportunities”
11.15 - 11.45 AM Tea
11.45 – 1.30 PM Session IX Free Oral Presentations of selected abstracts
Chairperson: Dr.Tanuja Teni
Selected Abstracts :
  • “Transcriptional Regulation of Cyclin D1 with onset and progression of Hepatocarcinogenesis”– Dr.Sanjay Gupta, ACTREC, Mumbai
  • “Novel route to anhydro-deoxy xylo and arabino sugars for conjugation”. – Dr.Sanjay Gupta, Dev Bhoomi Group Of Institution, Uttarakhand
  • “Role of Bioluminescence imaging in Cancer chemoprevention : Evidence for NF-kB inhibition in colon cancer by Dietary Compound”- Dr.Nabendu Murmu, Chittaranjan National Cancer Institute, Kalkata
  • “p53, p63, and p73 inhibit migrating cancer stem cells by activating stem cell suppressing miRNAs” – Dr.Lakshmanane Boominathan , Genome Discovery Unit, Pondicherry
  • “Stemcell and chemokine therapy for cancer : Ex-vivo expansion of human CD34+ cells manipulated with a mixture of cytokines and stromal cell derived Factor 1”- Dr.Jyoti Kode, Dr. B.R. Ambedkar Centre for Bio-medical Research, Delhi
  • “Down regulation of ETC Complex I Activity Promotes Epithelial Tumor Cell Invasiveness” – Leyon Varghese, Institute of Molecular and Cell Biology, Singapore
  • “Toxicogenomics of chromate carcinogenesis and its biological Annotations”- Sushil Kumar, Indian Institute of Toxicology Research, Lucknow
  • “Resveratrol induces apoptosis in human uveal melanoma cells” – Dr.Jasbir Kaur, All India Institute of Medical Sciences , New Delhi
  • “Members of myeloid translocation gene family (MTG), the putative tumor suppressors, function as co-repressors in modulation of Wnt-signaling” – Damen Saluja, Dr. B.R. Ambedkar Centre for Bio-medical Research, Delhi
1.30 - 2.30 PM Lunch
2.30 – 4.00 PM Session X Micro RNA & Cancer
Chairperson: Prof.A.Dharmarajan
2.30 – 3.00 PM Dr. N. Saini
IGIB, Delhi
“miRNAs as modulators of apoptosis”
3.00- 3.30 PM Dr.S.Krishnakumar
Sankara Nethralaya, Chennai
“Evolution of Prognostic Markers for Uveal Melanoma from the Light Microscopy days to the Current microRNA: An Ocular Pathologist’s Perspective”
3.30- 4.00 PM Dr. Dileep Vasudevan
“The Nucleosome Core Particle – simple stories from a complex structure”
4.00 PM Prize Distribution & Valedictory Function
4.30 PM High Tea