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The scientific goal of ACNS under the currently funded
program is to develop affordable products of high quality
that utilizes the novel properties of nanomaterials. This
is in keeping with the philosophy of Amrita. The Amrita
Centre for Nanosciences focuses on tissue engineering
and stem cell research using nanomaterials. The Centre
now also has funded programs in cancer diagnostics
and drug delivery using nanoparticles, nanosurface
modification of biomaterials for implant applications,
nanotoxicology, and processing of nanostructured thin
films for sensors and photovoltaic applications. The
Centre has state-of-the-art laboratories in nanoprocessing
and nanocharacterization. |
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Our research includes:
- Novel tissue engineered material replacements for
human tissues, including bone, skin, cartilage.
- Organ development using tissue engineering
- Development of novel nanomaterials for medical
diagnostics and drug delivery.
- Nano bio surface modification of materials
- Development of nano materials for energy
generation and storage
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| RESEARCH LABORATORIES |
The following research laboratories have been established:
- High Resolution Microscopy Lab with a high resolution
Scanning Electron Microscope and an Atomic Force
Microscope with a surface nanoprofiler
- Nanochemistry Lab for wet chemical processing of
nanomaterials and nanoparticles with centrifuges, electronic
balances, magnetic stirrers, oil/water baths and hoods
- Mechanical Testing Lab with a servohydraulic
computer controlled MTS testing facility for mechanical
characterization
- Chemical, Thermal and Size Characterization Lab with FTIR, UV-Vis Spectrophotometer, Differ ential Scanning
Calorimeter (DSC), a Gel Permeation Chromatograph
(GPC) and a Laser Nanoparticle Sizer with zeta potential
measurements capability
- Polymer Chemistry Lab for processing of polymer
nanomaterials
- Nanofiber and Surface Modification Lab with
electrospinning and electrochemical work station, as well as
surface polishing equipment
- Polymer Processing Lab for melt processing of
nanocomposites
- Cell Culture and Stem Cell Lab with FACS, inverted
microscope reader, CO2 incubator
- X-ray Diffraction Lab
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| CURRENT RESEARCH PROJECTS |
The following are briefs on the current research projects:
The Primary funding is for the “Centre for Nanotechnology – Tissue Engineering and Stem Cell Research”
funded by the Department of Science and Technology (DST) through the Nanoscience and Nanotechnology Initiative of
the Government of India. Under this program research is being conducted on processing of biodegradable polymeric
scaffolds with chemical and structural biofunctionality so as to be cell inductive, conductive and proliferative. The primary
focus is on bone tissue engineering using stem cells.
Nanosurface bioengineering of implants is a project funded by the Department of Biotechnology (DBT), the
Government of India and research focuses on provided surface nanostructures and combined surface nanostructural and
chemical modifications to improve biocompatibility. The emphasis is on Ti surface modification
Development of semiconductor nanoparticles for early detection of cancer is a project funded by the DBT.
This research focuses on development of multifunctional quantum dots that are biofunctionalised so as to target oral
cancer cells. The quantum dots are dopedso as to provide adequate luminescence to enable imaging of the targeted
cancer cells.
Nanotoxicology is also a DBT funded project. Under this project different
classes of nanoparticles are evaluated for their toxicity in a comprehensive
fashion to include cytotoxicity, inflammatory responses, cancer-causing
potential or tumerogencity, biodistribution and excretion. The project also
focuses on methods of pacifying the toxicity of nanoparticles.
Processing of nanostructured thin films for photovoltaic
applications is a DST sanctioned project. Research is conducted on
methods to simultaneously deposit and anodize thin films in single step
operation so as to obtain nanostructured thin films with novel electrical
and electromechanical properties.
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