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The scientific goal of ACNS under the currently funded program is to develop affordable products of high quality that utilizes the novel properties of nanomaterials. This is in keeping with the philosophy of Amrita. The Amrita Centre for Nanosciences focuses on tissue engineering and stem cell research using nanomaterials. The Centre now also has funded programs in cancer diagnostics and drug delivery using nanoparticles, nanosurface modification of biomaterials for implant applications, nanotoxicology, and processing of nanostructured thin films for sensors and photovoltaic applications. The Centre has state-of-the-art laboratories in nanoprocessing and nanocharacterization.
    Our research includes:

  • Novel tissue engineered material replacements for human tissues, including bone, skin, cartilage.
  • Organ development using tissue engineering
  • Development of novel nanomaterials for medical
    diagnostics and drug delivery.
  • Nano bio surface modification of materials
  • Development of nano materials for energy
    generation and storage
RESEARCH LABORATORIES
    The following research laboratories have been established:
  • High Resolution Microscopy Lab with a high resolution Scanning Electron Microscope and an Atomic Force
    Microscope with a surface nanoprofiler
  • Nanochemistry Lab for wet chemical processing of nanomaterials and nanoparticles with centrifuges, electronic
    balances, magnetic stirrers, oil/water baths and hoods
  • Mechanical Testing Lab with a servohydraulic computer controlled MTS testing facility for mechanical
    characterization
  • Chemical, Thermal and Size Characterization Lab with FTIR, UV-Vis Spectrophotometer, Differ ential Scanning Calorimeter (DSC), a Gel Permeation Chromatograph (GPC) and a Laser Nanoparticle Sizer with zeta potential
    measurements capability
  • Polymer Chemistry Lab for processing of polymer nanomaterials
  • Nanofiber and Surface Modification Lab with electrospinning and electrochemical work station, as well as
    surface polishing equipment
  • Polymer Processing Lab for melt processing of nanocomposites
  • Cell Culture and Stem Cell Lab with FACS, inverted microscope reader, CO2 incubator
  • X-ray Diffraction Lab
CURRENT RESEARCH PROJECTS

The following are briefs on the current research projects:

The Primary funding is for the “Centre for Nanotechnology – Tissue Engineering and Stem Cell Research
funded by the Department of Science and Technology (DST) through the Nanoscience and Nanotechnology Initiative of the Government of India. Under this program research is being conducted on processing of biodegradable polymeric scaffolds with chemical and structural biofunctionality so as to be cell inductive, conductive and proliferative. The primary focus is on bone tissue engineering using stem cells.


Nanosurface bioengineering of implants is a project funded by the Department of Biotechnology (DBT), the
Government of India and research focuses on provided surface nanostructures and combined surface nanostructural and
chemical modifications to improve biocompatibility. The emphasis is on Ti surface modification

Development of semiconductor nanoparticles for early detection of cancer is a project funded by the DBT. This research focuses on development of multifunctional quantum dots that are biofunctionalised so as to target oral cancer cells. The quantum dots are dopedso as to provide adequate luminescence to enable imaging of the targeted cancer cells.

Nanotoxicology is also a DBT funded project. Under this project different classes of nanoparticles are evaluated for their toxicity in a comprehensive fashion to include cytotoxicity, inflammatory responses, cancer-causing potential or tumerogencity, biodistribution and excretion. The project also focuses on methods of pacifying the toxicity of nanoparticles.


Processing of nanostructured thin films for photovoltaic applications is a DST sanctioned project. Research is conducted on methods to simultaneously deposit and anodize thin films in single step operation so as to obtain nanostructured thin films with novel electrical and electromechanical properties.

 
 
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